Журнал исследований фармацевтики и доставки лекарств

Physicochemical Properties of Co-Precipitate of Plantain Peel Cellulose and Gelatin

Orji JI, Akpa PA and Adikwu MU

Physicochemical Properties of Co-Precipitate of Plantain Peel Cellulose and Gelatin

Abstract

Cellulose was obtained from plantain peel by the soda pulping and the yield was 8%. The gelatin and cellulose were mixed in proportion of 1:1, 1:2 and 1:4. Avicel PH 101 was the standard. In this study, the compressibility%, hausner quotient and angle of repose for 1:1 was 13.5%, 1.16, 32° respectively while for 1:2 it was 17.6%, 1.21 and 38° respectively and 1:4 was 24.4%, 1.32 and 42° respectively. Avicel PH 101 had compressibility 37.1%, Hausner quotient 1.59 and angle of repose 60°. This means that 1:1 had a good flow, 1:2 had a fair flow and 1:4 had a passable flow and Avicel PH 101 had a very poor flow. The % solubility for 1:1, 1:2, 1:4 and Avicel PH 101 were 55.17%, 49.31%, 25.8% and10.98% respectively. The viscosity value for 1:1, 1:2, 1:4 and Avicel PH 101 is 8.257mpas, 6.738mpas, 5.146mpas and 4.622mpas respectively. From the values above, Avicel had the lowest % solubility, viscosity and poor flow while 1:1 had the highest % solubility, viscosity and good flow properties than others which mean that gelatin improved those properties.