Архивы клинической патологии

American Pathology and Oncology Research 2018- Survivin and caspase-3 as diagnostic and predictive biomarkers of recurrence for urinary bladder carcinoma after transurethral resection of bladder tumor

Vivian GD Rouston Amal AA Shaaban Dina M Abd Allah Ahmed F Kotb

Bladder most cancers even in early stage expand recurrence. Poor sensitivity of cytology and invasiveness of urethrocystoscopy have generated hobby in non-invasive tools to monitor for recurrence. Caspase-three and survivin have a significant role in the regulation of apoptosis. Survivin can aid early diagnosis, determine prognosis in a couple of most cancers types and predict reaction to anti-most cancers therapies. Its mixture with different biomarkers as caspase-three enhance prognostication and prediction of remedy response in Urinary Bladder Cancer or Carcinoma (UBC).