Журнал клинической иммунологии и исследований

Recognize Conserved Features of Pathogens

Thomas Clayton Coleman

Pathogen Recognition Receptors (PRRs) ar a category of germ line-encoded receptors that acknowledge infectious agent-Associated Molecular Patterns (PAMPs). The activation of PRRs is crucial for the initiation of immunity, that plays a key role in first-line defense till additional specific adaptive immunity is developed. Microorganisms do often breach the animal tissue barricades. it's then up to the innate and adaptive immune systems to acknowledge and destroy them, while not harming the host. Consequently, the immune systems should be ready to distinguish self from nonself. We tend to discuss in Chapter twenty four however the adaptive system.