Журнал фармацевтических наук и новых лекарств

Preparation and Assessment of Sunscreen Cream Containing Extract Acquired from Plant Origin

Nandkishore, Ashish Manigauha* and Balkrishna Dubey  

The objective of the current study was to formulate and investigate herbal sunscreen cream comprising extracts of plant origin such as Bacopa monnieri, Glycyrrhiza glabra and Daucus carota. The petroleum ether, ethanol and aqueous extracts of Bacopa monnieri, Glycyrrhiza glabra and Daucus carota were prepared. The ethanol and aqueous extracts were performed for total polyphenol and flavonoid content. The sunscreen herbal cream H1, H2 and H3 were formulated by incorporating different ratio of ethanol extracts, and further it was evaluated to check the stability of cream. The in vitro SPF values of prepared cream were studied. The stability studies of herbal formulations were performed for the period of three month. The ethanol extracts of Bacopa monnieri, Glycyrrhiza glabra and Daucus carota exhibited the highest total phenolic and flavonol content. The findings of pH, viscosity, spread ability, irritant study, acid value, saponification value and visualization of physical changing of cream were under limit and acceptable. From results of in vitro SPF, it was observed that the H1, H2 and H3 produce moderate to high SPF value ranges from 17.42 to 19.25. The F2 cream demonstrated higher SPF value as compared to H1 and H2 creams. The accelerated stability studies exhibited that formulation H1, H2 and H3 showed no changes in colour, consistency, spreadibilty, pH, viscosity and phase separation after storing at different conditions for about 3 months. Therefore, these formulations were considered as stable cream. The formulated sunscreen creams were nontoxic for skin.