Журнал клинических дерматологических исследований

A Rarely Seen Entity: Morbus Morbihan Disease

Ayse Akbas, Fadime Kilinc, Sibel Orhun Yavuz, Sertac Sener and Ak?n Aktas

Morbus Morbihan disease is granulomatous complication characterized with facial edema occuring due to acne or rosacea. It is resistant to treatment; diagnosis could be difficult. 48 years old male patient applied to our polyclinic with complaint of swelling on left side of his face, around his eye and cheeks, persistent for 6 months. He previously applied to dermatology, dental and Otorhinolaryngology departments in various hospitals but no diagnosis could be made. There was no trauma, exposure to sun, drug use history or symptoms like pain and itch. He was complaining about visual swelling. He had edema stretching from left side of his face to orbital area and mild erythema in his dermatological examination. Our pathology department reevaluated biopsy preparations taken by the center he previously went. Rosacea lymphedema was reported. Doxycycline, ornidazole, ketotifen and flutamide were administered by assuming that patient has Morbus Morbihan disease. In the next examination after one month, it has been observed that edema was diminished. In fourth month, edema decreased a lot. Thus treatment was stopped. The patient was applied again in the following 2 months due to increase at edema on his face. That time 0.5 mg/day isotretinoin treatment started and at third month edema regressed. We found this case appropriate to present to emphasize that it is rare and that it should be considered