Avinash Vallepalli, Rohit Patil and Kamalksh Shenoy
The incidence of intracranial germinomas is less than 1% of all intracranial neoplasms. Germinomas do not commonly occur in a suprasellar location. The presence of diabetes insipidus and visual disturbance as an early symptom has been reported in almost all patients of suprasellar germinomas and may help in distinguishing these tumours from other suprasellar lesions, Radiological studies such as MRI and biochemical markers help in the diagnosis of germinoma. Although they are extremely radiosensitive, chemotherapeutic agents aid in shrinking the tumour and reducing irradiated volume Which is particularly important in younger children to avoid post-irradiation endocrinological disturbances.
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